Hello, Can Dilute F100 be made from locally available products when the commercial F100 is not available?
Hi Anonymous,
Hypothetically yes. Practically I would urge extreme caution. As a first step you should contact your local authorities to liaise with UNICEF on supplying the appropriate commercial formulation. Home made recipes have a relatively high osmolarity compared to commercial formulas.
Please read a reply to a similar post from Professor Michale Golden. It is important to note the potential clinical consequences and the skilled staff needed to manage the child.
https://www.en-net.org/question/75.aspx
Professor Golden writes:
"First, F100 cannot be converted to F75, the proportions of the ingredients are quite different. Second, for both F100 and F75 the home-made recipies are MADE UP TO one litre of multiples thereoff. The comercial preparations not the same they are ADDED TO 2 Litres of water. This difference is often not appreciated. When I designed F100 and F75 and then wrote the WHO 1999 manual I stiputated the final volume to be 1000ml. However, in the field it was found to be quite difficult to see the final volume because of the froth (foam) on top that formed during mixing - so there was a change so that the powder was added to a fixed amount of water. Third, the commercial preparation of F75 is very difficult to emulate with home made recipies. The correct formula uses 35g of cereal powder and 70g of sugar. The problem with this formulation is that it becomes quite viscous and is difficult to put down an NG tube. For this reason one of the subesquent advisors to WHO suggested using 100g of sugar instead of the cereal powder. The problem now is that the formulation is hyperosmolar and frequently provokes an osmotic diarrhoea (we had about 12 deaths in Somalia due to this problem when the local staff started to use sugar instead of the cereal powder). If this osmotic diarrhoea is misdiagnosed as infective diarrhoea and treated with resomal then the children get an overload of sodium and go into heart failure. For this reason the formulation using sugar alone is dangerous unless all the staff clearly understand the reason and can correctly differentiate osmotic diarrhoea (no or trivial weight loss) from infective diarrhoea (weight loss if to be treated with rehydration fluids). For these reasons we strongly advocate for the use of the commercial preparation of F75 - relatively small amounts are needed. F75 was designed for the severe cases with liver dysfunction, sepsis, intestinal problems - and particularly for those with kwash. If there are limited supplies of the commercial formulation then, whilst more are being secured, they can be reserved for this type of child who will require NG tube feeding. The children who are not so severely ill can indeed be managed with diluted F100. The problem being that such changes in the protocol to suit pipeline breaks can cause confusion amongst the staff."
WHO provide recipes for various formulations here:
https://apps.who.int/iris/bitstream/handle/10665/205172/B0003.pdf?sequence=1&isAllowed=y
Other recipes are here:
https://motherchildnutrition.org/malnutrition-management/info/feeding-formulas-f75-f100.html
I hope this helps,
Paul
Answered:
2 years agoThanks a lot Anonymus for the question and Paul for the answer. This is interesting as some country may have - even with UNICEF in place - some shortage this year due to the conflict and complications. This may as well impact f75 which can complicate well the management case...
Answered:
2 years ago@ Paul, Thank you for the response very informative.
Currently there has been a shortage of commercial therapeutic feeds where I am. Thus for management of SAM cases we have to prepare the feeds from locally available products cautiously, However we have a challenge on preparing DILUTED F100 for the under 6 months SAM children because we don't have the recipe unlike F75 and F100 that is well documented on the IMAM guidelines.
Answered:
2 years ago@ Chantal Autotte Bouchard, Thanks for the response.
Yes actually we are facing shortage of commercial therepeutic feeds, so we have to prepare them for continuity of care.
Answered:
2 years agoDear all , please find the formula for making F100 and F75 from local available products , I remember in Afghanistan we were using these formula , when for some time we did not had , commercial F100 or F75 .
F75 and F 100 milk preparation guide reference Afghanistan Nutrition Standard Operation procedure book 2015
If you have kitchen/cooking facility and the ingredients, you can make the F75 recipes as follow:
Type of milk
Content
Quantity for F75
Dry milk without oil
Dry milk without lipid
25 mg
sugar
70 mg
Flour of cereals
30 mg
Vegetable oil
30 mg
CMV Complex mineral and Vitamins
20 ml
Water total 1000 cc
water1000 ml
Dry full milk
Dry full milk
35 mg
sugar
70 mg
Flour of cereals
35 mg
Vegetable oil
20 mg
CMV Complex mineral and Vitamins
20 ml
Water total 1000 cc
water1000 ml
Fresh cow full /whole milk
Fresh cow full /whole milk
300 ml
sugar
70 mg
Flour of cereals
35 mg
Vegetable oil
20 mg
CMV Complex mineral and Vitamins
20 ml
Water total 1000 cc
water1000 ml
If cereals flour is not available or cooking / kitchen facility is not available , You can use one of the following recipes for F75
Type of milk
Content
Quantity for F75
Quantity for F100
Dry milk without oil
Dry milk without lipid
25 gr
80 gr
sugar
100 gr
50 gr
Vegetable oil
30 gr
60 gr
CMV Complex mineral and Vitamins
20 ml
20 ml
Water total 1000 cc
water 1000 CC
water 1000 CC
Dry full milk
Dry full milk
35 g
110 gr
sugar
100 gr
50 gr
Vegetable oil
20 ml
30 gr
CMV Complex mineral and Vitamins
20 ml
20 ml
Water total 1000 cc
water1000 ml
water1000 ml
Fresh cow full /whole milk
Fresh cow full /whole milk
300 ml
880 ml
sugar
100 gr
75 gr
Vegetable oil
20 gr
20 gr
CMV Complex mineral and Vitamins
20 ml
20 ml
Water total 1000 cc
water1000 ml
water1000 ml
Note: adding water is very important recipe to recipe, the total amount should be 1000 ml, if you are using a measuring utensils is the best, hygiene is very important during the preparation and when you are keeping it for hours.
Answered:
2 years ago@ Dr. M Asef Ghyasi. Thanks for your response.
Did you by any chance make F100 Dilute?
Answered:
2 years ago